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limma

Linear Models for Microarray and Omics Data

Bioconductor version: 3.24 · Package version: 3.99.0

Data analysis, linear models and differential expression for omics data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("limma")

Details

MaintainerGordon Smyth <smyth@wehi.edu.au>
AuthorGordon Smyth [cre, aut] (ORCID: <https://orcid.org/0000-0001-9221-2892>), Lizhong Chen [aut] (ORCID: <https://orcid.org/0000-0002-8326-6781>), Yifang Hu [ctb], Matthew Ritchie [ctb], Jeremy Silver [ctb], James Wettenhall [ctb], Davis McCarthy [ctb], Di Wu [ctb], Wei Shi [ctb], Belinda Phipson [ctb], Aaron Lun [ctb], Yunshun Chen [ctb], Mengbo Li [ctb], Natalie Thorne [ctb], Carolyn de Graaf [ctb], Goknur Giner [ctb], Charity Law [ctb], Alicia Oshlack [ctb], Mette Langaas [ctb], Egil Ferkingstad [ctb], Marcus Davy [ctb], Francois Pepin [ctb], Dongseok Choi [ctb]
LicenseGPL (>=2)
URLhttps://bioinf.wehi.edu.au/limma/
Downloads rank42915
Source branchdevel
biocViewsAlternativeSplicing, BatchEffect, Bayesian, BiomedicalInformatics, CellBiology, Cheminformatics, Clustering, DataImport, DifferentialExpression, DifferentialSplicing, Epigenetics, ExonArray, FunctionalGenomics, GeneExpression, GeneSetEnrichment, Genetics, ImmunoOncology, Metabolomics, MicroRNAArray, Microarray, MultipleComparison, Normalization, OneChannel, Preprocessing, ProprietaryPlatforms, Proteomics, QualityControl, RNASeq, Regression, Sequencing, Software, SystemsBiology, TimeCourse, Transcription, Transcriptomics, TwoChannel, mRNAMicroarray

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagelimma_3.99.0.tar.gz
Windows binary (x86_64)limma_3.99.0.zip
macOS binary (arm64)limma_3.99.0.tgz
macOS binary (x86_64)limma_3.99.0.tgz
Dependencies

Depends: R (>= 3.6.0)

Imports: grDevices, graphics, stats, utils, methods, statmod

Suggests: BiasedUrn, ellipse, gplots, knitr, locfit, MASS, splines, affy, AnnotationDbi, Biobase, BiocStyle, GO.db, illuminaio, org.Hs.eg.db, SummarizedExperiment, vsn

Reverse dependencies

Depends On Me (55): AgiMicroRna, ASpli, BALLI, BioInsight, BLMA, CCl4, CEDA, cghMCR, ChimpHumanBrainData, clippda, codelink, convert, Cormotif, cp4p, DAAGbio, DEqMS, DRomics, DrugVsDisease, edgeR, EGSEA123, ExiMiR, ExpressionAtlas, Fletcher2013a, fmt, HD2013SGI, HTqPCR, IsoformSwitchAnalyzeR, limpa, maEndToEnd, maPredictDSC, marray, metagenomeSeq, metaseqR2, methylationArrayAnalysis, mpra, NanoTube, octad, PerfMeas, protGear, qpcrNorm, qusage, RBM, ReactomeGSA.data, RNAseq123, RnBeads, Rnits, splineTimeR, TMSig, TOAST, tRanslatome, ttScreening, TurboNorm, variancePartition, wateRmelon, zenith

Imports Me (273): a4Base, ABSSeq, affycoretools, affylmGUI, AMARETTO, animalcules, anota2seq, ArrayExpress, arrayQuality, arrayQualityMetrics, artMS, ATACseqQC, ATACseqTFEA, attract, augere.de, augere.gsea, augere.screen, autonomics, AWFisher, barbieQ, BatChef, BatchQC, batchtma, beadarray, BeadArrayUseCases, benchdamic, BERT, biotmle, BloodGen3Module, bnem, BPM, bsseq, bumphunter, Cascade, casper, ChAMP, cinaR, CleanUpRNAseq, clusterExperiment, CNVRanger, combi, compcodeR, CONFESS, consensusOV, crlmm, csaw, cTRAP, ctsGE, DAMEfinder, damidBind, DaMiRseq, daVis, debrowser, DeeDeeExperiment, DELocal, derfinderPlot, DESpace, DEsubs, DExMA, DiffBind, diffcyt, diffHic, diffUTR, diffwrap, DiPALM, distinct, DMRcate, dnaEPICO, Doscheda, dreamlet, DRIMSeq, dsb, DspikeIn, EGAD, EGSEA, eisaR, eLNNpairedCov, EnrichmentBrowser, epigraHMM, EpiMix, erccdashboard, EventPointer, EWCE, ExpHunterSuite, ExploreModelMatrix, ExpressionNormalizationWorkflow, flowBin, gCrisprTools, GDCRNATools, genefu, GeneSelectMMD, GEOquery, GExPipe, gg4way, gINTomics, Glimma, GRaNIE, GSEAlens, GSEMA, GUIDEseq, GWAS.BAYES, GWASbyCluster, HarmonizR, hermes, HERON, hicream, hipathia, HTqPCR, icetea, iCheck, iChip, iCOBRA, ideal, InPAS, isomiRs, KnowSeq, lemur, lfproQC, lilikoi, limmaGUI, limorhyde2, LimROTS, Linnorm, LIPIDIFy, lipidomeR, lipidr, lmdme, markeR, mastR, MatrixQCvis, MBECS, MBQN, mCSEA, MEAL, MetAlyzer, metaMA, MetaProViz, methylKit, MethylMix, mi4p, microbiomeExplorer, miloR, minfi, MIRit, miRLAB, miRtest, missMethyl, MKmisc, MKomics, MLSeq, monocle, MoonlightR, MSclassifR, msImpute, mspms, msqrob2, MSstats, MSstatsTMT, MultiDataSet, MultiOmicsBridge, muscat, mutscan, NADfinder, NanoMethViz, nethet, netZooR, newIMVC, nlcv, nondetects, NormalyzerDE, notameViz, OLIN, omicRexposome, oncoPredict, OncoSubtype, OVESEG, PAA, PADOG, pairedGSEA, PanomiR, PathoStat, Patterns, pcaExplorer, PECA, PepSetTest, pepStat, phantasus, phenomis, phenoTest, PhosR, plfMA, PolySTest, POMA, POWSC, proBatch, projectR, promor, PRONE, ProteinBatcher, psichomics, qmtools, qPLEXanalyzer, qsea, RANKS, rCGH, RCPA, recountWorkflow, RegEnrich, regsplice, ReportingTools, RFGeneRank, RFLOMICS, RNAseqCovarImpute, roastgsa, robusttseq, ROSeq, RPPanalyzer, RTN, RTopper, saseR, satuRn, scBio, scClassify, scCompoundDE, scFastDE, scGOclust, scone, scQTLtools, scran, ScreenR, scROSHI, seqsetvis, shinyDSP, shinyepico, signatureSearchData, singleCellTK, SmartPhos, sparrow, spatialLIBD, speckle, SpNeigh, SPsimSeq, ssizeRNA, standR, STATegRa, Statial, structToolbox, sva, TiDEomics, tidyexposomics, timecourse, tinyarray, TOP, ToxicoGx, TPP, TPP2D, TraianProt, transcriptogramer, TransProR, treediff, TVTB, tweeDEseq, unifiedWMWqPCR, VISTA, vsclust, vsn, weitrix, Wrench, wrProteo, XAItest, XYomics, yamss, yarn

Suggests Me (122): ABarray, ADaCGH2, AnnoProbe, aroma.affymetrix, arrays, augere.core, Biobase, BiocSet, BioNet, BioQC, blase, BloodCancerMultiOmics2017, broadSeq, bugphyzz, CAGEWorkflow, canvasXpress, Category, categoryCompare, celaref, CellBench, CellMixS, ChIPpeakAnno, ClassifyR, CMA, coGPS, CONSTANd, corncob, cydar, Damsel, DAPAR, DaparToolshed, dar, DAssemble, dearseq, DEGreport, derfinder, DEScan2, DGEobj.utils, dyebias, easybio, easyreporting, EnMCB, extraChIPs, fgsea, fishpond, fluentGenomics, gage, GeoTcgaData, GeuvadisTranscriptExpr, geva, ggpicrust2, GiANT, glmGamPoi, GSRI, GSVA, Harman, Heatplus, hexbin, inDAGO, IOBR, iSEEde, isobar, ivygapSE, les, levi, limorhyde, lionessR, lumi, maGUI, mammaPrintData, MAST, methylumi, MLP, MosaiClusteR, msigdb, NACHO, normScore, npGSEA, oligo, oppar, pctax, piano, pmartR, PREDA, proDA, protti, puma, QFeatures, qsvaR, raer, randRotation, recountmethylation, RepeatedHighDim, ribosomeProfilingQC, rtracklayer, Rvisdiff, scFeatures, seqgendiff, Seurat, SeuratExplorer, seventyGeneData, signifinder, simphony, simpleSingleCell, spatialHeatmap, SpliceWiz, st, stageR, subSeq, systemPipeR, tadar, TCGAbiolinks, TFEA.ChIP, tidybulk, topconfects, tximeta, tximport, ViSEAGO, volcano3D, wrGraph, wrMisc, zFPKM