msImpute

Imputation of label-free mass spectrometry peptides

Bioconductor version: 3.24 · Package version: 1.23.0

MsImpute is a package for imputation of peptide intensity in proteomics experiments. It additionally contains tools for MAR/MNAR diagnosis and assessment of distortions to the probability distribution of the data post imputation. The missing values are imputed by low-rank approximation of the underlying data matrix if they are MAR (method = "v2"), by Barycenter approach if missingness is MNAR ("v2-mnar"), or by Peptide Identity Propagation (PIP).

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("msImpute")