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rCGH

Comprehensive Pipeline for Analyzing and Visualizing Array-Based CGH Data

Bioconductor version: 3.24 · Package version: 1.43.0

A comprehensive pipeline for analyzing and interactively visualizing genomic profiles generated through commercial or custom aCGH arrays. As inputs, rCGH supports Agilent dual-color Feature Extraction files (.txt), from 44 to 400K, Affymetrix SNP6.0 and cytoScanHD probeset.txt, cychp.txt, and cnchp.txt files exported from ChAS or Affymetrix Power Tools. rCGH also supports custom arrays, provided data complies with the expected format. This package takes over all the steps required for individual genomic profiles analysis, from reading files to profiles segmentation and gene annotations. This package also provides several visualization functions (static or interactive) which facilitate individual profiles interpretation. Input files can be in compressed format, e.g. .bz2 or .gz.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("rCGH")

Details

MaintainerFrederic Commo <fredcommo@gmail.com>
AuthorFrederic Commo [aut, cre]
LicenseArtistic-2.0
URLhttps://github.com/fredcommo/rCGH
Downloads rank801
Source branchdevel
biocViewsCopyNumberVariation, FeatureExtraction, Preprocessing, Software, aCGH

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagerCGH_1.43.0.tar.gz
Windows binary (x86_64)rCGH_1.43.0.zip
macOS binary (arm64)rCGH_1.43.0.tgz
macOS binary (x86_64)rCGH_1.43.0.tgz
Dependencies

Depends: R (>= 3.4), methods, stats, utils, graphics

Imports: plyr, DNAcopy, lattice, ggplot2, grid, shiny (>= 0.11.1), limma, affy, mclust, TxDb.Hsapiens.UCSC.hg18.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, GenomicFeatures, Seqinfo, GenomicRanges, AnnotationDbi, parallel, IRanges, grDevices, aCGH

Suggests: BiocStyle, knitr, BiocGenerics, RUnit

Reverse dependencies

Imports Me (1): preciseTAD