methylumi
Handle Illumina methylation data
Bioconductor version: 3.24 · Package version: 2.59.3
This package provides classes for holding and manipulating Illumina methylation data. Based on eSet, it can contain MIAME information, sample information, feature information, and multiple matrices of data. An "intelligent" import function, methylumiR can read the Illumina text files and create a MethyLumiSet. methylumIDAT can directly read raw IDAT files from HumanMethylation27 and HumanMethylation450 microarrays. Normalization, background correction, and quality control features for GoldenGate, Infinium, and Infinium HD arrays are also included.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("methylumi") Details
| Maintainer | Sean Davis <seandavi@gmail.com> |
| Author | Sean Davis, Pan Du, Sven Bilke, Tim Triche, Jr., Moiz Bootwalla |
| License | GPL-2 |
| URL | https://seandavi.github.io/methylumi/, https://github.com/seandavi/methylumi |
| Bug Reports | https://github.com/seandavi/methylumi/issues |
| Downloads rank | 2210 |
| Source branch | devel |
| biocViews | CpGIsland, DNAMethylation, Preprocessing, QualityControl, Software, TwoChannel |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | methylumi_2.59.3.tar.gz |
| Windows binary (x86_64) | methylumi_2.59.3.zip |
| macOS binary (arm64) | methylumi_2.59.3.tgz |
| macOS binary (x86_64) | methylumi_2.59.3.tgz |
Dependencies
Depends: Biobase, methods, R (>= 4.0), scales, reshape2, ggplot2, matrixStats, FDb.InfiniumMethylation.hg19 (>= 2.2.0), minfi
Imports: BiocGenerics, S4Vectors, IRanges, GenomeInfoDb, GenomicRanges, SummarizedExperiment, Biobase, graphics, grDevices, stats, utils, lattice, annotate, genefilter, AnnotationDbi, minfi, stats4, illuminaio, GenomicFeatures, BiocParallel
Suggests: lumi, limma, SQN, MASS, rtracklayer, Biostrings, quarto, TCGAMethylation450k, IlluminaHumanMethylation450kanno.ilmn12.hg19, FDb.InfiniumMethylation.hg18 (>= 2.2.0), Homo.sapiens, TxDb.Hsapiens.UCSC.hg19.knownGene, knitr, testthat (>= 3.0.0)
Reverse dependencies
Depends On Me (4): bigmelon, RnBeads, skewr, wateRmelon
Imports Me (3): ffpe, lumi, missMethyl