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LIPIDIFy

Comprehensive Lipidomics Data Analysis with Interactive Visualization

Bioconductor version: 3.24 · Package version: 0.99.7

Provides a comprehensive toolkit for end-to-end lipidomics data analysis, including missing value imputation, batch effect correction, normalization, differential abundance analysis using limma and edgeR, gene set enrichment analysis, and extensive visualization capabilities. Lipid names are automatically classified by class, subclass, and fatty-acid saturation. Features both an interactive Shiny interface for bench biologists and fully scriptable R functions for bioinformaticians. Supports flexible custom lipid classification schemes and user-defined enrichment sets.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("LIPIDIFy")

Details

MaintainerFayrouz Hammal <fayrouz.hammal@petermac.org>
AuthorFayrouz Hammal [aut, cre] (ORCID: <https://orcid.org/0000-0002-7612-4953>), Karen Sheppard [fnd] (NHMRC of Australia grant #2020050)
LicenseMIT + file LICENSE
URLhttps://github.com/fayrouzhammal/LIPIDIFy
Bug Reportshttps://github.com/fayrouzhammal/LIPIDIFy/issues
Source branchdevel
biocViewsBatchEffect, Classification, DataImport, DifferentialExpression, GeneSetEnrichment, Lipidomics, MassSpectrometry, MultipleComparison, Normalization, Preprocessing, QualityControl, ShinyApps, Software, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageLIPIDIFy_0.99.7.tar.gz
Windows binary (x86_64)LIPIDIFy_0.99.7.zip
macOS binary (arm64)LIPIDIFy_0.99.7.tgz
macOS binary (x86_64)LIPIDIFy_0.99.7.tgz
Dependencies

Depends: R (>= 4.5.0)

Imports: shiny (>= 1.8.0), shinydashboard, ggplot2 (>= 3.5.0), ggrepel, plotly, DT, tidyr, dplyr, scales, gridExtra, grid, pheatmap, limma, edgeR, fgsea, FactoMineR, pls, openxlsx, rmarkdown, stringr, withr, utils, stats, grDevices

Suggests: BiocStyle, knitr, testthat (>= 3.0.0), impute, sva, vsn, SummarizedExperiment, tinytex, shinytest2, chromote