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skewr

Visualize Intensities Produced by Illumina's Human Methylation 450k BeadChip

Bioconductor version: 3.24 · Package version: 1.45.0

The skewr package is a tool for visualizing the output of the Illumina Human Methylation 450k BeadChip to aid in quality control. It creates a panel of nine plots. Six of the plots represent the density of either the methylated intensity or the unmethylated intensity given by one of three subsets of the 485,577 total probes. These subsets include Type I-red, Type I-green, and Type II.The remaining three distributions give the density of the Beta-values for these same three subsets. Each of the nine plots optionally displays the distributions of the "rs" SNP probes and the probes associated with imprinted genes as series of 'tick' marks located above the x-axis.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("skewr")

Details

MaintainerRyan Putney <ryanputney@gmail.com>
AuthorRyan Putney [cre, aut], Steven Eschrich [aut], Anders Berglund [aut]
LicenseGPL-2
Downloads rank514
Source branchdevel
biocViewsDNAMethylation, Preprocessing, QualityControl, Software, TwoChannel

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageskewr_1.45.0.tar.gz
Windows binary (x86_64)skewr_1.45.0.zip
macOS binary (arm64)skewr_1.45.0.tgz
macOS binary (x86_64)skewr_1.45.0.tgz
Dependencies

Depends: R (>= 3.1.1), methylumi, wateRmelon, mixsmsn, IlluminaHumanMethylation450kmanifest

Imports: minfi, S4Vectors (>= 0.19.1), RColorBrewer

Suggests: GEOquery, knitr, minfiData