universalmotif
A Toolkit for Sequence Motif Analysis
Bioconductor version: 3.24 · Package version: 1.31.54
A comprehensive toolkit for working with sequence motifs in R. Imports and exports most common motif formats (JASPAR, MEME, HOMER, TRANSFAC, CIS-BP, UNIPROBE) and interoperates with the other Bioconductor motif packages. Analysis functions cover de novo motif discovery, motif-vs-motif comparison and clustering, P-value calculation, sequence scanning, enrichment against shuffled or composition-matched backgrounds, positional bias testing, and pairwise motif co-occurrence. Also includes utilities for sequence shuffling, motif trimming, higher-order representations, ground-truth simulation by motif implantation, and logo-plotting functionality.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("universalmotif") Details
| Maintainer | Benjamin Jean-Marie Tremblay <benjamin.tremblay@uwaterloo.ca> |
| Author | Benjamin Jean-Marie Tremblay [aut, cre] (ORCID: <https://orcid.org/0000-0002-7441-2951>), Sabrina Nystrom [ctb] (ORCID: <https://orcid.org/0000-0003-1000-1579>) |
| License | GPL-3 |
| URL | https://bioconductor.org/packages/universalmotif/ |
| Bug Reports | https://github.com/bjmt/universalmotif/issues |
| Downloads rank | 1770 |
| Source branch | devel |
| biocViews | DataImport, GeneRegulation, MotifAnnotation, MotifDiscovery, Software |
Documentation
- An end-to-end ChIP-seq workflow: from a peak BED to enriched motifs
- Building a curated motif database from multiple sources
- Introduction to "universalmotif"
- Introduction to sequence motifs
- Motif comparisons and P-values
- Motif import, export, and manipulation
- Sequence manipulation and scanning
Download
Follow the installation instructions to use this package in your R session.
| Source package | universalmotif_1.31.54.tar.gz |
| Windows binary (x86_64) | universalmotif_1.31.54.zip |
| macOS binary (arm64) | universalmotif_1.31.54.tgz |
| macOS binary (x86_64) | universalmotif_1.31.54.tgz |
Dependencies
Depends: R (>= 4.1.0)
Imports: methods, stats, utils, parallel, MASS, ggplot2, yaml, IRanges, Rcpp, Biostrings, BiocGenerics, S4Vectors, rlang, grid, grDevices, MatrixGenerics
LinkingTo: Rcpp, RcppThread
Suggests: spelling, knitr, bookdown, TFBSTools, rmarkdown, MotifDb, testthat, BiocParallel, seqLogo, motifStack, dplyr, ape, ggtree, processx, ggseqlogo, cowplot, GenomicRanges, GenomeInfoDb, ggbio, rtracklayer, BSgenome, BSgenome.Athaliana.TAIR.TAIR9
Reverse dependencies
Imports Me (6): ChIPpeakAnno, circRNAprofiler, memes, MotifPeeker, motifTestR, SEMPLR
Suggests Me (1): epiSeeker