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TFBSTools

Software Package for Transcription Factor Binding Site (TFBS) Analysis

Bioconductor version: 3.24 · Package version: 1.51.0

TFBSTools is a package for the analysis and manipulation of transcription factor binding sites. It includes matrices conversion between Position Frequency Matirx (PFM), Position Weight Matirx (PWM) and Information Content Matrix (ICM). It can also scan putative TFBS from sequence/alignment, query JASPAR database and provides a wrapper of de novo motif discovery software.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("TFBSTools")

Details

MaintainerGe Tan <ge_tan@live.com>
AuthorGe Tan [aut, cre]
LicenseGPL-2
URLhttps://github.com/ge11232002/TFBSTools
Bug Reportshttps://github.com/ge11232002/TFBSTools/issues
Downloads rank4231
Source branchdevel
biocViewsAlignment, GeneRegulation, MotifAnnotation, MotifDiscovery, Software, Transcription

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageTFBSTools_1.51.0.tar.gz
Windows binary (x86_64)TFBSTools_1.51.0.zip
macOS binary (arm64)TFBSTools_1.51.0.tgz
macOS binary (x86_64)TFBSTools_1.51.0.tgz
Dependencies

Depends: R (>= 3.2.2)

Imports: Biobase (>= 2.28), Biostrings (>= 2.36.4), pwalign, BiocGenerics (>= 0.14.0), BiocParallel (>= 1.2.21), BSgenome (>= 1.36.3), caTools (>= 1.17.1), DirichletMultinomial (>= 1.10.0), Seqinfo, GenomicRanges (>= 1.20.6), gtools (>= 3.5.0), grid, IRanges (>= 2.2.7), methods, DBI (>= 0.6), RSQLite (>= 1.0.0), rtracklayer (>= 1.28.10), seqLogo (>= 1.34.0), S4Vectors (>= 0.9.25), TFMPvalue (>= 0.0.5), XML (>= 3.98-1.3), XVector (>= 0.8.0), parallel

Suggests: BiocStyle (>= 1.7.7), JASPAR2014 (>= 1.4.0), knitr (>= 1.11), testthat, JASPAR2016 (>= 1.0.0), JASPAR2018 (>= 1.0.0), rmarkdown

Reverse dependencies

Imports Me (8): ATACseqTFEA, chromVAR, esATAC, MatrixRider, monaLisa, motifmatchr, motifStack, primirTSS

Suggests Me (11): CAGEWorkflow, enhancerHomologSearch, epiSeeker, GRaNIE, JASPAR2018, JASPAR2020, JASPAR2022, MAGAR, pageRank, Signac, universalmotif