DEXSeq
Inference of differential exon usage in RNA-Seq
Bioconductor version: 3.24 · Package version: 1.59.0
The package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DEXSeq") Details
| Maintainer | Hugo Gruson <hugo.gruson@embl.de> |
| Author | Simon Anders [aut], Alejandro Reyes [aut, ccp] (Maintainer until 2026.), Hugo Gruson [cre] |
| License | GPL (>= 3) |
| Downloads rank | 2359 |
| Source branch | devel |
| biocViews | AlternativeSplicing, DifferentialExpression, DifferentialSplicing, GeneExpression, ImmunoOncology, RNASeq, Sequencing, Software, Visualization |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | DEXSeq_1.59.0.tar.gz |
| Windows binary (x86_64) | DEXSeq_1.59.0.zip |
| macOS binary (arm64) | DEXSeq_1.59.0.tgz |
| macOS binary (x86_64) | DEXSeq_1.59.0.tgz |
Dependencies
Depends: BiocParallel, Biobase, SummarizedExperiment, IRanges (>= 2.5.17), GenomicRanges (>= 1.23.7), DESeq2 (>= 1.39.6), AnnotationDbi, S4Vectors (>= 0.23.18)
Imports: BiocGenerics, biomaRt, hwriter, methods, stringr, Rsamtools, statmod, geneplotter, genefilter
Suggests: GenomeInfoDb, GenomicFeatures, txdbmaker, pasilla (>= 0.2.22), BiocStyle, knitr, rmarkdown, testthat, pasillaBamSubset, GenomicAlignments, roxygen2, glmGamPoi
Reverse dependencies
Depends On Me (3): IsoformSwitchAnalyzeR, pasilla, rnaseqDTU
Imports Me (3): diffUTR, IntEREst, pairedGSEA
Suggests Me (6): bambu, BioPlex, GenomicRanges, satuRn, stageR, subSeq