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DSS

Dispersion shrinkage for sequencing data

Bioconductor version: 3.24 · Package version: 2.61.0

DSS is an R library performing differntial analysis for count-based sequencing data. It detectes differentially expressed genes (DEGs) from RNA-seq, and differentially methylated loci or regions (DML/DMRs) from bisulfite sequencing (BS-seq). The core of DSS is a new dispersion shrinkage method for estimating the dispersion parameter from Gamma-Poisson or Beta-Binomial distributions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DSS")

Details

MaintainerHao Wu <hao.wu@emory.edu>, Hao Feng <hxf155@case.edu>
AuthorHao Wu<hao.wu@emory.edu>, Hao Feng<hxf155@case.edu>
LicenseGPL
Downloads rank1322
Source branchdevel
biocViewsDNAMethylation, DifferentialExpression, DifferentialMethylation, GeneExpression, RNASeq, Sequencing, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageDSS_2.61.0.tar.gz
Windows binary (x86_64)DSS_2.61.0.zip
macOS binary (arm64)DSS_2.61.0.tgz
macOS binary (x86_64)DSS_2.61.0.tgz
Dependencies

Depends: R (>= 3.5.0), methods, Biobase, BiocParallel, bsseq, parallel

Imports: utils, graphics, stats, splines

Suggests: BiocStyle, knitr, rmarkdown, edgeR

Reverse dependencies

Imports Me (4): borealis, kissDE, metaseqR2, methylSig

Suggests Me (2): methrix, PROPER