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srnadiff

Finding differentially expressed unannotated genomic regions from RNA-seq data

Bioconductor version: 3.24 · Package version: 1.33.0

srnadiff is a package that finds differently expressed regions from RNA-seq data at base-resolution level without relying on existing annotation. To do so, the package implements the identify-then-annotate methodology that builds on the idea of combining two pipelines approachs differential expressed regions detection and differential expression quantification. It reads BAM files as input, and outputs a list differentially regions, together with the adjusted p-values.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("srnadiff")

Details

MaintainerZytnicki Matthias <matthias.zytnicki@inra.fr>
AuthorZytnicki Matthias [aut, cre], Gonzalez Ignacio [aut]
LicenseGPL-3
System RequirementsC++11
Downloads rank518
Source branchdevel
biocViewsCoverage, DifferentialExpression, Epigenetics, GeneExpression, ImmunoOncology, Preprocessing, SmallRNA, Software, StatisticalMethod

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagesrnadiff_1.33.0.tar.gz
Windows binary (x86_64)srnadiff_1.33.0.zip
macOS binary (arm64)srnadiff_1.33.0.tgz
macOS binary (x86_64)srnadiff_1.33.0.tgz
Dependencies

Depends: R (>= 3.6)

Imports: Rcpp (>= 0.12.8), stats, methods, S4Vectors, Seqinfo, rtracklayer, SummarizedExperiment, IRanges, GenomicRanges, DESeq2, edgeR, Rsamtools, GenomicFeatures, GenomicAlignments, grDevices, Gviz, BiocParallel, BiocManager, BiocStyle

LinkingTo: Rcpp

Suggests: knitr, rmarkdown, testthat, BiocManager, BiocStyle