panoramic

Variance-Aware Multi-Sample Spatial Colocalization Analysis

Bioconductor version: 3.24 · Package version: 0.99.3

Quantifies and compares cell-type spatial colocalization across samples, patients, and conditions in spatial omics studies. Its primary statistic, edge-corrected local competition enrichment, measures excess or deficit local mixing for ordered cell-type pairs on a percentage-point scale. The package estimates within-sample uncertainty with spatial bootstrap procedures and propagates it through multilevel random-effects meta-analysis for pooled inference and group-level contrasts; classical spatial summary statistics are also supported.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("panoramic")