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netSmooth

Network smoothing for scRNAseq

Bioconductor version: 3.24 · Package version: 1.33.0

netSmooth is an R package for network smoothing of single cell RNA sequencing data. Using bio networks such as protein-protein interactions as priors for gene co-expression, netsmooth improves cell type identification from noisy, sparse scRNAseq data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("netSmooth")

Details

MaintainerJonathan Ronen <yablee@gmail.com>
AuthorJonathan Ronen [aut, cre], Altuna Akalin [aut]
LicenseGPL-3
URLhttps://github.com/BIMSBbioinfo/netSmooth
Bug Reportshttps://github.com/BIMSBbioinfo/netSmooth/issues
Downloads rank531
Source branchdevel
biocViewsClustering, DimensionReduction, GeneExpression, GraphAndNetwork, Network, Normalization, Preprocessing, RNASeq, Sequencing, SingleCell, Software, Transcriptomics

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagenetSmooth_1.33.0.tar.gz
Windows binary (x86_64)netSmooth_1.33.0.zip
macOS binary (arm64)netSmooth_1.33.0.tgz
macOS binary (x86_64)netSmooth_1.33.0.tgz
Dependencies

Depends: R (>= 3.5), scater (>= 1.15.11), clusterExperiment (>= 2.1.6)

Imports: entropy, SummarizedExperiment, SingleCellExperiment, Matrix, cluster, data.table, stats, methods, DelayedArray, HDF5Array (>= 1.15.13)

Suggests: knitr, testthat, Rtsne, biomaRt, igraph, STRINGdb, NMI, pheatmap, ggplot2, BiocStyle, rmarkdown, BiocParallel, uwot