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MethylAid

Visual and interactive quality control of large Illumina DNA Methylation array data sets

Bioconductor version: 3.24 · Package version: 1.47.0

A visual and interactive web application using RStudio's shiny package. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MethylAid")

Details

MaintainerL.J.Sinke <L.J.Sinke@lumc.nl>
AuthorMaarten van Iterson [aut, cre], Elmar Tobi[ctb], Roderick Slieker[ctb], Wouter den Hollander[ctb], Rene Luijk[ctb] and Bas Heijmans[ctb]
LicenseGPL (>= 2)
Downloads rank680
Source branchdevel
biocViewsBatchEffect, DNAMethylation, GUI, MethylationArray, Microarray, QualityControl, Software, TwoChannel, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageMethylAid_1.47.0.tar.gz
Windows binary (x86_64)MethylAid_1.47.0.zip
macOS binary (arm64)MethylAid_1.47.0.tgz
macOS binary (x86_64)MethylAid_1.47.0.tgz
Dependencies

Depends: R (>= 3.4)

Imports: Biobase, BiocParallel, BiocGenerics, ggplot2, grid, gridBase, grDevices, graphics, hexbin, matrixStats, minfi (>= 1.22.0), methods, RColorBrewer, shiny, stats, SummarizedExperiment, utils

Suggests: BiocStyle, knitr, MethylAidData, minfiData, minfiDataEPIC, RUnit

Reverse dependencies

Depends On Me (1): MethylAidData