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IsoformSwitchAnalyzeR

Identify, Annotate and Visualize Isoform Switches with Functional Consequences from both short- and long-read RNA-seq data

Bioconductor version: 3.24 · Package version: 2.13.0

Analysis of alternative splicing and isoform switches with predicted functional consequences (e.g. gain/loss of protein domains etc.) from quantification of all types of RNA-seq (short/long) by tools such as Kallisto, Salmon, StringTie, Tallon, IsoQuant etc.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("IsoformSwitchAnalyzeR")

Details

MaintainerKristoffer Vitting-Seerup <k.vitting.seerup@gmail.com>
AuthorKristoffer Vitting-Seerup [cre, aut] (ORCID: <https://orcid.org/0000-0002-6450-0608>), Chunxu Han [ctb], Jeroen Gilis [ctb] (ORCID: <https://orcid.org/0000-0001-8415-0943>), Elena Iriondo Delgado [ctb]
LicenseGPL (>= 2)
URLhttp://bioconductor.org/packages/IsoformSwitchAnalyzeR/
Bug Reportshttps://github.com/kvittingseerup/IsoformSwitchAnalyzeR/issues
Downloads rank982
Source branchdevel
biocViewsAlternativeSplicing, Annotation, BatchEffect, BiomedicalInformatics, DataImport, DifferentialExpression, DifferentialSplicing, FunctionalGenomics, FunctionalPrediction, GeneExpression, GenePrediction, ImmunoOncology, MultipleComparison, RNASeq, Software, StatisticalMethod, SystemsBiology, Transcription, TranscriptomeVariant, Transcriptomics, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageIsoformSwitchAnalyzeR_2.13.0.tar.gz
Windows binary (x86_64)IsoformSwitchAnalyzeR_2.13.0.zip
macOS binary (arm64)IsoformSwitchAnalyzeR_2.13.0.tgz
macOS binary (x86_64)IsoformSwitchAnalyzeR_2.13.0.tgz
Dependencies

Depends: R (>= 4.2), limma, DEXSeq, satuRn (>= 1.7.0), sva, ggplot2 (>= 3.3.5), pfamAnalyzeR

Imports: methods, BSgenome, plyr, reshape2, gridExtra, Biostrings (>= 2.50.0), IRanges, GenomicRanges, RColorBrewer, rtracklayer, VennDiagram, DBI, grDevices, graphics, stats, utils, Seqinfo, grid, tximport (>= 1.7.1), tximeta (>= 1.7.12), edgeR, futile.logger, stringr, dplyr, magrittr, readr, tibble, XVector, BiocGenerics, RCurl, Biobase, SummarizedExperiment, tidyr, S4Vectors, BiocParallel, pwalign

Suggests: knitr, BSgenome.Hsapiens.UCSC.hg19, rmarkdown