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crisprBwa

BWA-based alignment of CRISPR gRNA spacer sequences

Bioconductor version: 3.24 · Package version: 1.17.0

Provides a user-friendly interface to map on-targets and off-targets of CRISPR gRNA spacer sequences using bwa. The alignment is fast, and can be performed using either commonly-used or custom CRISPR nucleases. The alignment can work with any reference or custom genomes. Currently not supported on Windows machines.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("crisprBwa")

Details

MaintainerJean-Philippe Fortin <fortin946@gmail.com>
AuthorJean-Philippe Fortin [aut, cre]
LicenseMIT + file LICENSE
URLhttps://github.com/crisprVerse/crisprBwa
Bug Reportshttps://github.com/crisprVerse/crisprBwa/issues
Downloads rank298
Source branchdevel
biocViewsAlignment, CRISPR, FunctionalGenomics, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagecrisprBwa_1.17.0.tar.gz
macOS binary (arm64)crisprBwa_1.17.0.tgz
macOS binary (x86_64)crisprBwa_1.17.0.tgz
Dependencies

Depends: methods

Imports: BiocGenerics, BSgenome, crisprBase (>= 0.99.15), Seqinfo, Rbwa, readr, stats, stringr, utils

Suggests: BiocStyle, BSgenome.Hsapiens.UCSC.hg38, knitr, rmarkdown, testthat

Reverse dependencies

Suggests Me (1): crisprDesign