MPRAnalyze
Statistical Analysis of MPRA data
Bioconductor version: 3.24 · Package version: 1.31.0
MPRAnalyze provides statistical framework for the analysis of data generated by Massively Parallel Reporter Assays (MPRAs), used to directly measure enhancer activity. MPRAnalyze can be used for quantification of enhancer activity, classification of active enhancers and comparative analyses of enhancer activity between conditions. MPRAnalyze construct a nested pair of generalized linear models (GLMs) to relate the DNA and RNA observations, easily adjustable to various experimental designs and conditions, and provides a set of rigorous statistical testig schemes.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MPRAnalyze")Details
| Maintainer | Tal Ashuach <tal_ashuach@berkeley.edu> |
| Author | Tal Ashuach [aut, cre], David S Fischer [aut], Anat Kriemer [ctb], Fabian J Theis [ctb], Nir Yosef [ctb], |
| License | GPL-3 |
| URL | https://github.com/YosefLab/MPRAnalyze |
| Bug Reports | https://github.com/YosefLab/MPRAnalyze |
| Downloads rank | 434 |
| Source branch | devel |
| biocViews | CellBasedAssays, CellBiology, Classification, DifferentialExpression, ExperimentalDesign, GeneExpression, ImmunoOncology, Sequencing, Software, StatisticalMethod |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | MPRAnalyze_1.31.0.tar.gz |
| Windows binary (x86_64) | MPRAnalyze_1.31.0.zip |
| macOS binary (arm64) | MPRAnalyze_1.31.0.tgz |
| macOS binary (x86_64) | MPRAnalyze_1.31.0.tgz |