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CoGAPS

Coordinated Gene Activity in Pattern Sets

Bioconductor version: 3.24 · Package version: 3.33.0

Coordinated Gene Activity in Pattern Sets (CoGAPS) implements a Bayesian MCMC matrix factorization algorithm, GAPS, and links it to gene set statistic methods to infer biological process activity. It can be used to perform sparse matrix factorization on any data, and when this data represents biomolecules, to do gene set analysis.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CoGAPS")

Details

MaintainerElana J. Fertig <ejfertig@jhmi.edu>, Thomas D. Sherman <tomsherman159@gmail.com>, Jeanette Johnson <jjohn450@jhmi.edu>, Dmitrijs Lvovs <dlvovs1@jh.edu>
AuthorJeanette Johnson, Ashley Tsang, Jacob Mitchell, Thomas Sherman, Wai-shing Lee, Conor Kelton, Ondrej Maxian, Jacob Carey, Genevieve Stein-O'Brien, Michael Considine, Maggie Wodicka, John Stansfield, Shawn Sivy, Carlo Colantuoni, Alexander Favorov, Mike Ochs, Elana Fertig
LicenseBSD_3_clause + file LICENSE
Downloads rank659
Source branchdevel
biocViewsBayesian, Clustering, DifferentialExpression, DimensionReduction, GeneExpression, GeneSetEnrichment, ImmunoOncology, Microarray, MultipleComparison, RNASeq, Software, TimeCourse, Transcription

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageCoGAPS_3.33.0.tar.gz
Windows binary (x86_64)CoGAPS_3.33.0.zip
macOS binary (arm64)CoGAPS_3.33.0.tgz
macOS binary (x86_64)CoGAPS_3.33.0.tgz
Dependencies

Depends: R (>= 3.5.0)

Imports: BiocParallel, cluster, methods, gplots, graphics, grDevices, RColorBrewer, Rcpp, S4Vectors, SingleCellExperiment, stats, SummarizedExperiment, tools, utils, rhdf5, dplyr, fgsea, forcats, ggplot2

LinkingTo: Rcpp, BH, testthat

Suggests: testthat, knitr, rmarkdown, BiocStyle, SeuratObject, BiocFileCache, xml2

Reverse dependencies

Suggests Me (2): projectR, SpaceMarkers