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CNAnorm

A normalization method for Copy Number Aberration in cancer samples

Bioconductor version: 3.24 · Package version: 1.59.0

Performs ratio, GC content correction and normalization of data obtained using low coverage (one read every 100-10,000 bp) high troughput sequencing. It performs a "discrete" normalization looking for the ploidy of the genome. It will also provide tumour content if at least two ploidy states can be found.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CNAnorm")

Details

MaintainerStefano Berri <sberri@illumina.com>
AuthorStefano Berri <sberri@illumina.com>, Henry M. Wood <H.M.Wood@leeds.ac.uk>, Arief Gusnanto <a.gusnanto@leeds.ac.uk>
LicenseGPL-2
URLhttp://www.r-project.org,
Downloads rank471
Source branchdevel
biocViewsCopyNumberVariation, Coverage, DNASeq, GenomicVariation, Normalization, Sequencing, Software, WholeGenome

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageCNAnorm_1.59.0.tar.gz
Windows binary (x86_64)CNAnorm_1.59.0.zip
macOS binary (arm64)CNAnorm_1.59.0.tgz
macOS binary (x86_64)CNAnorm_1.59.0.tgz
Dependencies

Depends: R (>= 2.10.1), methods

Imports: DNAcopy