Bioc2026 Registration Open!

safe

Significance Analysis of Function and Expression

Bioconductor version: 3.23 · Package version: 3.52.1

SAFE is a resampling-based method for testing functional categories in gene expression experiments. SAFE can be applied to 2-sample and multi-class comparisons, or simple linear regressions. Other experimental designs can also be accommodated through user-defined functions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("safe")

Details

MaintainerLudwig Geistlinger <ludwig.geistlinger@gmail.com>
AuthorWilliam T. Barry
LicenseGPL (>= 2)
Downloads rank1204
Source branchRELEASE_3_23
biocViewsDifferentialExpression, GeneSetEnrichment, Pathways, Software, StatisticalMethod

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagesafe_3.52.1.tar.gz
Windows binary (x86_64)safe_3.52.1.zip
macOS binary (arm64)safe_3.52.1.tgz
macOS binary (x86_64)safe_3.52.1.tgz
Dependencies

Depends: R (>= 2.4.0), AnnotationDbi, Biobase, methods, SparseM

Suggests: GO.db, PFAM.db, reactome.db, hgu133a.db, breastCancerUPP, survival, foreach, doRNG, Rgraphviz, GOstats

Reverse dependencies

Imports Me (2): EGSEA, EnrichmentBrowser

Suggests Me (1): ReporterScore