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isobar

Analysis and quantitation of isobarically tagged MSMS proteomics data

Bioconductor version: 3.23 · Package version: 1.58.0

isobar provides methods for preprocessing, normalization, and report generation for the analysis of quantitative mass spectrometry proteomics data labeled with isobaric tags, such as iTRAQ and TMT. Features modules for integrating and validating PTM-centric datasets (isobar-PTM). More information on http://www.ms-isobar.org.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("isobar")

Details

MaintainerFlorian P Breitwieser <florian.bw@gmail.com>
AuthorFlorian P Breitwieser <florian.bw@gmail.com> and Jacques Colinge <jacques.colinge@inserm.fr>, with contributions from Alexey Stukalov <stukalov@biochem.mpg.de>, Xavier Robin <xavier.robin@unige.ch> and Florent Gluck <florent.gluck@unige.ch>
LicenseLGPL-2
URLhttps://github.com/fbreitwieser/isobar
Bug Reportshttps://github.com/fbreitwieser/isobar/issues
Downloads rank715
Source branchRELEASE_3_23
biocViewsBioinformatics, ImmunoOncology, MassSpectrometry, MultipleComparisons, Proteomics, QualityControl, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageisobar_1.58.0.tar.gz
Windows binary (x86_64)isobar_1.58.0.zip
macOS binary (arm64)isobar_1.58.0.tgz
macOS binary (x86_64)isobar_1.58.0.tgz
Dependencies

Depends: R (>= 2.10.0), Biobase, stats, methods

Imports: distr, plyr, biomaRt, ggplot2

Suggests: MSnbase, OrgMassSpecR, XML, RJSONIO, Hmisc, gplots, RColorBrewer, gridExtra, limma, boot, DBI, MASS