SPIA
Signaling Pathway Impact Analysis (SPIA) using combined evidence of pathway over-representation and unusual signaling perturbations
Bioconductor version: 3.23 · Package version: 2.64.0
This package implements the Signaling Pathway Impact Analysis (SPIA) which uses the information form a list of differentially expressed genes and their log fold changes together with signaling pathways topology, in order to identify the pathways most relevant to the condition under the study.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("SPIA")Details
| Maintainer | Adi Laurentiu Tarca <atarca@med.wayne.edu> |
| Author | Adi Laurentiu Tarca <atarca@med.wayne.edu>, Purvesh Kathri <purvesh@cs.wayne.edu> and Sorin Draghici <sorin@wayne.edu> |
| License | file LICENSE |
| URL | http://bioinformatics.oxfordjournals.org/cgi/reprint/btn577v1 |
| Downloads rank | 1408 |
| Source branch | RELEASE_3_23 |
| biocViews | GraphAndNetwork, Microarray, Software |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | SPIA_2.64.0.tar.gz |
| Windows binary (x86_64) | SPIA_2.64.0.zip |
| macOS binary (arm64) | SPIA_2.64.0.tgz |
| macOS binary (x86_64) | SPIA_2.64.0.tgz |
Dependencies
Depends: R (>= 2.14.0), graphics, KEGGgraph
Imports: graphics
Suggests: graph, Rgraphviz, hgu133plus2.db