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InTAD

Search for correlation between epigenetic signals and gene expression in TADs

Bioconductor version: 3.23 · Package version: 1.32.0

The package is focused on the detection of correlation between expressed genes and selected epigenomic signals (i.e. enhancers obtained from ChIP-seq data) either within topologically associated domains (TADs) or between chromatin contact loop anchors. Various parameters can be controlled to investigate the influence of external factors and visualization plots are available for each analysis step.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("InTAD")

Details

MaintainerKonstantin Okonechnikov <k.okonechnikov@gmail.com>
AuthorKonstantin Okonechnikov, Serap Erkek, Lukas Chavez
LicenseGPL (>=2)
Downloads rank511
Source branchRELEASE_3_23
biocViewsChIPSeq, Epigenetics, GeneExpression, HiC, ImmunoOncology, RNASeq, Sequencing, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageInTAD_1.32.0.tar.gz
Windows binary (x86_64)InTAD_1.32.0.zip
macOS binary (arm64)InTAD_1.32.0.tgz
macOS binary (x86_64)InTAD_1.32.0.tgz
Dependencies

Depends: R (>= 3.5), methods, S4Vectors, IRanges, GenomicRanges, MultiAssayExperiment, SummarizedExperiment, stats

Imports: BiocGenerics, Biobase, rtracklayer, parallel, graphics, mclust, qvalue, ggplot2, utils, ggpubr

Suggests: testthat, BiocStyle, knitr, rmarkdown