InTAD
Search for correlation between epigenetic signals and gene expression in TADs
Bioconductor version: 3.23 · Package version: 1.32.0
The package is focused on the detection of correlation between expressed genes and selected epigenomic signals (i.e. enhancers obtained from ChIP-seq data) either within topologically associated domains (TADs) or between chromatin contact loop anchors. Various parameters can be controlled to investigate the influence of external factors and visualization plots are available for each analysis step.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("InTAD") Details
| Maintainer | Konstantin Okonechnikov <k.okonechnikov@gmail.com> |
| Author | Konstantin Okonechnikov, Serap Erkek, Lukas Chavez |
| License | GPL (>=2) |
| Downloads rank | 511 |
| Source branch | RELEASE_3_23 |
| biocViews | ChIPSeq, Epigenetics, GeneExpression, HiC, ImmunoOncology, RNASeq, Sequencing, Software |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | InTAD_1.32.0.tar.gz |
| Windows binary (x86_64) | InTAD_1.32.0.zip |
| macOS binary (arm64) | InTAD_1.32.0.tgz |
| macOS binary (x86_64) | InTAD_1.32.0.tgz |
Dependencies
Depends: R (>= 3.5), methods, S4Vectors, IRanges, GenomicRanges, MultiAssayExperiment, SummarizedExperiment, stats
Imports: BiocGenerics, Biobase, rtracklayer, parallel, graphics, mclust, qvalue, ggplot2, utils, ggpubr