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CrispRVariants

Tools for counting and visualising mutations in a target location

Bioconductor version: 3.23 · Package version: 1.40.0

CrispRVariants provides tools for analysing the results of a CRISPR-Cas9 mutagenesis sequencing experiment, or other sequencing experiments where variants within a given region are of interest. These tools allow users to localize variant allele combinations with respect to any genomic location (e.g. the Cas9 cut site), plot allele combinations and calculate mutation rates with flexible filtering of unrelated variants.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CrispRVariants")

Details

MaintainerHelen Lindsay <helen.lindsay@chuv.ch>
AuthorHelen Lindsay [aut, cre]
LicenseGPL-2
Downloads rank697
Source branchRELEASE_3_23
biocViewsCRISPR, DataRepresentation, GeneticVariability, GenomicVariation, ImmunoOncology, Sequencing, Software, VariantDetection, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageCrispRVariants_1.40.0.tar.gz
Windows binary (x86_64)CrispRVariants_1.40.0.zip
macOS binary (arm64)CrispRVariants_1.40.0.tgz
macOS binary (x86_64)CrispRVariants_1.40.0.tgz
Dependencies

Depends: R (>= 4.3.0), ggplot2 (>= 2.2.0)

Imports: AnnotationDbi, BiocParallel, Biostrings, methods, GenomeInfoDb, GenomicAlignments, GenomicRanges, grDevices, grid, gridExtra, IRanges, reshape2, Rsamtools, S4Vectors (>= 0.9.38), utils

Suggests: BiocStyle, GenomicFeatures, knitr, rmarkdown, readxl, rtracklayer, sangerseqR, testthat, VariantAnnotation