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nethet

A bioconductor package for high-dimensional exploration of biological network heterogeneity

Bioconductor version: 3.23 · Package version: 1.44.0

Package nethet is an implementation of statistical solid methodology enabling the analysis of network heterogeneity from high-dimensional data. It combines several implementations of recent statistical innovations useful for estimation and comparison of networks in a heterogeneous, high-dimensional setting. In particular, we provide code for formal two-sample testing in Gaussian graphical models (differential network and GGM-GSA; Stadler and Mukherjee, 2013, 2014) and make a novel network-based clustering algorithm available (mixed graphical lasso, Stadler and Mukherjee, 2013).

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("nethet")

Details

MaintainerNicolas Staedler <staedler.n@gmail.com>, Frank Dondelinger <fdondelinger.work@gmail.com>
AuthorNicolas Staedler, Frank Dondelinger
LicenseGPL-2
Downloads rank516
Source branchRELEASE_3_23
biocViewsClustering, GraphAndNetwork, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagenethet_1.44.0.tar.gz
Windows binary (x86_64)nethet_1.44.0.zip
macOS binary (arm64)nethet_1.44.0.tgz
macOS binary (x86_64)nethet_1.44.0.tgz
Dependencies

Imports: glasso, mvtnorm, GeneNet, huge, CompQuadForm, ggm, mclust, parallel, GSA, limma, multtest, ICSNP, glmnet, network, ggplot2, grDevices, graphics, stats, utils

Suggests: knitr, xtable, BiocStyle, testthat