PAA

PAA (Protein Array Analyzer)

Bioconductor version: 3.23 · Package version: 1.46.0

PAA imports single color (protein) microarray data that has been saved in gpr file format - esp. ProtoArray data. After preprocessing (background correction, batch filtering, normalization) univariate feature preselection is performed (e.g., using the "minimum M statistic" approach - hereinafter referred to as "mMs"). Subsequently, a multivariate feature selection is conducted to discover biomarker candidates. Therefore, either a frequency-based backwards elimination aproach or ensemble feature selection can be used. PAA provides a complete toolbox of analysis tools including several different plots for results examination and evaluation.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("PAA")