Bioc2026 Registration Open!

NestLink

NestLink an R data package to guide through Engineered Peptide Barcodes for In-Depth Analyzes of Binding Protein Ensembles

Bioconductor version: 3.24 · Package version: 1.29.0

Provides next-generation sequencing (NGS) and mass spectrometry (MS) sample data, code snippets and replication material used for developing NestLink. The NestLink approach is a protein binder selection and identification technology able to biophysically characterize thousands of library members at once without handling individual clones at any stage of the process. Data were acquired on NGS and MS platforms at the Functional Genomics Center Zurich.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("NestLink")

Details

MaintainerLennart Opitz <lopitz@fgcz.ethz.ch>
AuthorPascal Egloff [aut] (ORCID: <https://orcid.org/0000-0001-8948-3704>), Iwan Zimmermann [ctb] (ORCID: <https://orcid.org/0000-0003-3476-4749>), Fabian M. Arnold [ctb], Cedric A.J. Hutter [ctb] (ORCID: <https://orcid.org/0000-0002-8920-3343>), Lennart Opitz [aut, cre] (ORCID: <https://orcid.org/0000-0001-7945-6737>), Lucy Poveda [ctb] (ORCID: <https://orcid.org/0000-0002-5291-5582>), Hans-Anton Keserue [ctb], Christian Panse [aut, ctb] (ORCID: <https://orcid.org/0000-0003-1975-3064>), Bernd Roschitzki [aut] (ORCID: <https://orcid.org/0000-0001-5756-9773>), Markus Seeger [aut] (ORCID: <https://orcid.org/0000-0003-1761-8571>)
LicenseGPL
Downloads rank189
Source branchdevel
biocViewsExperimentData, ExperimentHub, MassSpectrometryData, ReproducibleResearch, SequencingData

Download

Follow the installation instructions to use this package in your R session.

Source packageNestLink_1.29.0.tar.gz
Dependencies

Depends: R (>= 3.6), AnnotationHub (>= 2.15), ExperimentHub (>= 1.0), Biostrings (>= 2.51), gplots (>= 3.0), protViz (>= 0.4), ShortRead (>= 1.41)

Imports: grDevices, graphics, stats, utils

Suggests: BiocStyle (>= 2.2), DT, ggplot2, knitr, rmarkdown, testthat, specL, lattice, scales