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sparsenetgls

Using Gaussian graphical structue learning estimation in generalized least squared regression for multivariate normal regression

Bioconductor version: 3.24 · Package version: 1.31.0

The package provides methods of combining the graph structure learning and generalized least squares regression to improve the regression estimation. The main function sparsenetgls() provides solutions for multivariate regression with Gaussian distributed dependant variables and explanatory variables utlizing multiple well-known graph structure learning approaches to estimating the precision matrix, and uses a penalized variance covariance matrix with a distance tuning parameter of the graph structure in deriving the sandwich estimators in generalized least squares (gls) regression. This package also provides functions for assessing a Gaussian graphical model which uses the penalized approach. It uses Receiver Operative Characteristics curve as a visualization tool in the assessment.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("sparsenetgls")

Details

MaintainerIrene Zeng <szen003@aucklanduni.ac.nz>
AuthorIrene Zeng [aut, cre], Thomas Lumley [ctb]
LicenseGPL-3
System RequirementsGNU make
Downloads rank342
Source branchdevel
biocViewsCopyNumberVariation, GraphAndNetwork, ImmunoOncology, MassSpectrometry, Metabolomics, Proteomics, Regression, Software, Visualization

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagesparsenetgls_1.31.0.tar.gz
Windows binary (x86_64)sparsenetgls_1.31.0.zip
macOS binary (arm64)sparsenetgls_1.31.0.tgz
macOS binary (x86_64)sparsenetgls_1.31.0.tgz
Dependencies

Depends: R (>= 4.0.0), Matrix, MASS

Imports: methods, glmnet, huge, stats, graphics, utils

Suggests: testthat, lme4, BiocStyle, knitr, rmarkdown, roxygen2 (>= 5.0.0)