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simPIC

Flexible simulation of paired-insertion counts for single-cell ATAC-sequencing data

Bioconductor version: 3.24 · Package version: 1.9.0

simPIC is a package for simulating single-cell ATAC-seq count data. It provides a user-friendly, well documented interface for data simulation. Functions are provided for parameter estimation, realistic scATAC-seq data simulation, and comparing real and simulated datasets.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("simPIC")

Details

MaintainerSagrika Chugh <sagrika.chugh@gmail.com>
AuthorSagrika Chugh [aut, cre] (<https://orcid.org/0000-0002-8050-5214>), Heejung Shim [aut], Davis McCarthy [aut]
LicenseGPL-3
URLhttps://github.com/sagrikachugh/simPIC
Bug Reportshttps://github.com/sagrikachugh/simPIC/issues
Downloads rank365
Source branchdevel
biocViewsATACSeq, DataImport, ImmunoOncology, Sequencing, SingleCell, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packagesimPIC_1.9.0.tar.gz
Windows binary (x86_64)simPIC_1.9.0.zip
macOS binary (arm64)simPIC_1.9.0.tgz
macOS binary (x86_64)simPIC_1.9.0.tgz
Dependencies

Depends: R (>= 4.5.0), SingleCellExperiment

Imports: BiocGenerics, checkmate (>= 2.0.0), fitdistrplus, matrixStats, actuar, Matrix, stats, SummarizedExperiment, rlang, S4Vectors, GenomeInfoDb, methods, scales, scuttle, edgeR, withr

Suggests: bluster, ggplot2 (>= 3.4.0), knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0), scater, scran, magick, splatter, VariantAnnotation, IRanges, GenomicRanges, preprocessCore