Uniquorn

Identification of cancer cell lines based on their weighted mutational/ variational fingerprint

Bioconductor version: 3.24 · Package version: 2.33.0

'Uniquorn' enables users to identify cancer cell lines. Cancer cell line misidentification and cross-contamination reprents a significant challenge for cancer researchers. The identification is vital and in the frame of this package based on the locations/ loci of somatic and germline mutations/ variations. The input format is vcf/ vcf.gz and the files have to contain a single cancer cell line sample (i.e. a single member/genotype/gt column in the vcf file).

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Uniquorn")