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RCAS

RNA Centric Annotation System

Bioconductor version: 3.24 · Package version: 1.39.0

RCAS is an R/Bioconductor package designed as a generic reporting tool for the functional analysis of transcriptome-wide regions of interest detected by high-throughput experiments. Such transcriptomic regions could be, for instance, signal peaks detected by CLIP-Seq analysis for protein-RNA interaction sites, RNA modification sites (alias the epitranscriptome), CAGE-tag locations, or any other collection of query regions at the level of the transcriptome. RCAS produces in-depth annotation summaries and coverage profiles based on the distribution of the query regions with respect to transcript features (exons, introns, 5'/3' UTR regions, exon-intron boundaries, promoter regions). Moreover, RCAS can carry out functional enrichment analyses and discriminative motif discovery.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RCAS")

Details

MaintainerBora Uyar <bora.uyar@mdc-berlin.de>
AuthorBora Uyar [aut, cre], Dilmurat Yusuf [aut], Ricardo Wurmus [aut], Altuna Akalin [aut]
LicenseArtistic-2.0
System Requirementspandoc (>= 1.12.3)
Downloads rank664
Source branchdevel
biocViewsCoverage, GO, GeneSetEnrichment, GeneTarget, GenomeAnnotation, MotifAnnotation, MotifDiscovery, Software, Transcriptomics

Download

Follow the installation instructions to use this package in your R session.

Source packageRCAS_1.39.0.tar.gz
Windows binary (x86_64)RCAS_1.39.0.zip
macOS binary (arm64)RCAS_1.39.0.tgz
macOS binary (x86_64)RCAS_1.39.0.tgz
Dependencies

Depends: R (>= 3.5.0), plotly (>= 4.5.2), DT (>= 0.2), data.table

Imports: GenomicRanges, IRanges, BSgenome, BSgenome.Hsapiens.UCSC.hg19, GenomeInfoDb (>= 1.12.0), Biostrings, rtracklayer, GenomicFeatures, txdbmaker, rmarkdown (>= 0.9.5), genomation (>= 1.5.5), knitr (>= 1.12.3), BiocGenerics, S4Vectors, plotrix, pbapply, RSQLite, proxy, pheatmap, ggplot2, cowplot, seqLogo, utils, ranger, gprofiler2

Suggests: testthat, covr, BiocManager

Reverse dependencies

Imports Me (1): GenomicPlot