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INDEED

Interactive Visualization of Integrated Differential Expression and Differential Network Analysis for Biomarker Candidate Selection Package

Bioconductor version: 3.24 · Package version: 2.27.0

An R package for integrated differential expression and differential network analysis based on omic data for cancer biomarker discovery. Both correlation and partial correlation can be used to generate differential network to aid the traditional differential expression analysis to identify changes between biomolecules on both their expression and pairwise association levels. A detailed description of the methodology has been published in Methods journal (PMID: 27592383). An interactive visualization feature allows for the exploration and selection of candidate biomarkers.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("INDEED")

Details

MaintainerRessom group <hwr@georgetown.edu>, Yiming Zuo <yimingzuo@gmail.com>
AuthorYiming Zuo <yimingzuo@gmail.com>, Kian Ghaffari <kg.ghaffari@gmail.com>, Zhenzhi Li <zzrickli@gmail.com>
LicenseArtistic-2.0
URLhttp://github.com/ressomlab/INDEED
Bug Reportshttp://github.com/ressomlab/INDEED/issues
Downloads rank307
Source branchdevel
biocViewsBiologicalQuestion, DifferentialExpression, ImmunoOncology, MassSpectrometry, Metabolomics, ResearchField, Software, StatisticalMethod

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageINDEED_2.27.0.tar.gz
Windows binary (x86_64)INDEED_2.27.0.zip
macOS binary (arm64)INDEED_2.27.0.tgz
macOS binary (x86_64)INDEED_2.27.0.tgz
Dependencies

Depends: glasso (>= 1.8), R (>= 3.5)

Imports: devtools (>= 1.13.0), graphics (>= 3.3.1), stats (>= 3.3.1), utils (>= 3.3.1), igraph (>= 1.2.4), visNetwork (>= 2.0.6)

Suggests: knitr (>= 1.19), rmarkdown (>= 1.8), testthat (>= 2.0.0)