DeMAND
DeMAND
Bioconductor version: 3.24 · Package version: 1.43.0
DEMAND predicts Drug MoA by interrogating a cell context specific regulatory network with a small number (N >= 6) of compound-induced gene expression signatures, to elucidate specific proteins whose interactions in the network is dysregulated by the compound.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DeMAND")Details
| Maintainer | Jung Hoon Woo <jw2853@columbia.edu>, Mariano Alvarez <reef103@gmail.com> |
| Author | Jung Hoon Woo <jw2853@columbia.edu>, Yishai Shimoni <ys2559@columbia.edu> |
| License | file LICENSE |
| Downloads rank | 321 |
| Source branch | devel |
| biocViews | GeneExpression, Network, NetworkEnrichment, Software, StatisticalMethod, SystemsBiology |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | DeMAND_1.43.0.tar.gz |
| Windows binary (x86_64) | DeMAND_1.43.0.zip |
| macOS binary (arm64) | DeMAND_1.43.0.tgz |
| macOS binary (x86_64) | DeMAND_1.43.0.tgz |
Dependencies
Depends: R (>= 2.14.0), KernSmooth, methods