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CexoR

An R package to uncover high-resolution protein-DNA interactions in ChIP-exo replicates

Bioconductor version: 3.24 · Package version: 1.51.0

Strand specific peak-pair calling in ChIP-exo replicates. The cumulative Skellam distribution function is used to detect significant normalised count differences of opposed sign at each DNA strand (peak-pairs). Then, irreproducible discovery rate for overlapping peak-pairs across biological replicates is computed.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CexoR")

Details

MaintainerPedro Madrigal <pmadrigal@ebi.ac.uk>
AuthorPedro Madrigal [aut, cre] (ORCID: <https://orcid.org/0000-0003-1959-8199>)
LicenseArtistic-2.0 | GPL-2 + file LICENSE
URLhttps://github.com/pmb59/CexoR
Bug Reportshttps://github.com/pmb59/CexoR/issues
Downloads rank636
Source branchdevel
biocViewsChIPSeq, Coverage, FunctionalGenomics, PeakDetection, Sequencing, Software

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageCexoR_1.51.0.tar.gz
Windows binary (x86_64)CexoR_1.51.0.zip
macOS binary (arm64)CexoR_1.51.0.tgz
macOS binary (x86_64)CexoR_1.51.0.tgz
Dependencies

Depends: R (>= 4.2.0), S4Vectors, IRanges

Imports: Rsamtools, Seqinfo, GenomicRanges, rtracklayer, idr, RColorBrewer, genomation

Suggests: RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown