detectionPnegNorm {sesame}R Documentation

Detection P-value based on normal fitting the negative controls

Description

The function takes a SigSet as input, computes detection p-value using negative control probes parametrized in a normal distribution and returns a new SigSet with an updated pval slot.

Usage

detectionPnegNorm(sset)

Arguments

sset

a SigSet

Details

Background of Grn and Red are estimated separately from negative control probes-parameterized normal distribution. p-value is taken from the minimum of the p-value of the two alleles (color depends on probe design).

Value

detection p-value

Examples

sset <- makeExampleSeSAMeDataSet()
sset <- detectionPnegNorm(sset)


[Package sesame version 1.2.0 Index]