detectionPnegNormGS {sesame} | R Documentation |
The function takes a SigSet
as input, computes detection p-value
using negative control probes parametrized in a normal distribution a la
Genome Studio and returns a new SigSet
with an updated pval slot.
detectionPnegNormGS(sset)
sset |
a |
P-value is calculated using negative control probes as the estimate of background where Grn channel and Red channel are merged. But when estimating p-value the Red and Grn are summed (non-ideal).
detection p-value
sset <- makeExampleSeSAMeDataSet() sset <- detectionPnegNormGS(sset)