estiGeneNBstat {SeqGSEA} | R Documentation |
Calculate NB-statistics quantifying differential splicing for each gene between two groups of samples compared. The results will be used for GSEA run (as DS-scores).
estiGeneNBstat(RCS)
RCS |
a ReadCountSet object after running |
A ReadCountSet object with slot featureData_gene
updated.
Please run estiExonNBstat
before run this function.
Xi Wang, xi.wang@newcastle.edu.au
Weichen Wang, Zhiyi Qin, Zhixing Feng, Xi Wang and Xuegong Zhang (2013). Identifying differentially spliced genes from two groups of RNA-seq samples. Gene, 518(1):164-170.
data(RCS_example, package="SeqGSEA") RCS_example <- exonTestability(RCS_example, cutoff=5) RCS_example <- estiExonNBstat(RCS_example) RCS_example <- estiGeneNBstat(RCS_example) head(RCS_example@featureData_gene)