CopyNumberModel {CNPBayes} | R Documentation |
The mixture components do not necessarily reflect distinct copy number
states, possibly due to skewed (non-Gaussian) log R ratios. While easy to fit skewed data with a finite mixture of Gaussians, additional steps are needed to assess whether the components correspond to distinct copy number states. This accessor copyNumber
returns the copy number states – i.e., the result after mapping mixture components to copy number states.
CopyNumberModel(model, params = mapParams()) SingleBatchCopyNumber(model) MultiBatchCopyNumber(model) MultiBatchCopyNumberPooled(model) ## S4 method for signature 'SingleBatchModel' CopyNumberModel(model, params = mapParams()) ## S4 method for signature 'MultiBatchModel' CopyNumberModel(model, params = mapParams()) ## S4 method for signature 'MultiBatchPooled' CopyNumberModel(model, params = mapParams()) mapCopyNumber(model, params = mapParams())
model |
a SB, SBP, MB, or MBP model |
params |
a list of parameters used for mapping mixture components to copy number states. |
a MultiBatchCopyNumber
instance
a MultiBatchCopyNumber
instance
sb <- SingleBatchModelExample cn.model <- CopyNumberModel(sb, mapParams())