splatSimDropout {splatter} | R Documentation |
A logistic function is used to form a relationshop between the expression level of a gene and the probability of dropout, giving a probability for each gene in each cell. These probabilities are used in a Bernoulli distribution to decide which counts should be dropped.
splatSimDropout(sim, params)
sim |
SingleCellExperiment to add dropout to. |
params |
SplatParams object with simulation parameters. |
SingleCellExperiment with simulated dropout and observed counts.