mpraSetExample {mpra} | R Documentation |
Example data for the MPRA package. The package contains data both at the barcode level and aggregated over barcodes. The data comes from a study by Inoue et al that compares episomal and lentiviral MPRA.
data("mpraSetExample") data("mpraSetAggExample")
An MPRASet
.
mpraSetExample
contains barcode level information.
mpraSetAggExample
contains count information where the counts
have been summed over barcodes for each element.
A script from creating the two datasets are supplied in the
scripts
folder of the package. The data is taken from the GEO
submission associated with the paper (see references), specifically
GSE83894.
Inoue, Fumitaka, Martin Kircher, Beth Martin, Gregory M. Cooper, Daniela M. Witten, Michael T. McManus, Nadav Ahituv, and Jay Shendure. A Systematic Comparison Reveals Substantial Differences in Chromosomal versus Episomal Encoding of Enhancer Activity. Genome Research 2017, 27(1):38-52. doi: 10.1101/gr.212092.116.
data(mpraSetAggExample)