computeAmax {PharmacoGx} | R Documentation |
Fits dose-response curves to data given by the user and returns the Amax of the fitted curve. Amax: 100 - viability at maximum concentarion (in fitted curve)
computeAmax(concentration, viability, trunc = TRUE, verbose = FALSE)
concentration |
[vector] is a vector of drug concentrations. |
viability |
[vector] is a vector whose entries are the viability values observed in the presence of the drug concentrations whose logarithms are in the corresponding entries of the log_conc, expressed as percentages of viability in the absence of any drug. |
trunc |
[logical], if true, causes viability data to be truncated to lie between 0 and 1 before curve-fitting is performed. |
verbose |
[logical] should warnings be printed |
The numerical Amax
dose <- c("0.0025","0.008","0.025","0.08","0.25","0.8","2.53","8") viability <- c("108.67","111","102.16","100.27","90","87","74","57") computeAmax(dose, viability)