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rnaseqDTU

RNA-seq workflow for differential transcript usage following Salmon quantification

Bioconductor version: 3.24 · Package version: 1.33.0

RNA-seq workflow for differential transcript usage (DTU) following Salmon quantification. This workflow uses Bioconductor packages tximport, DRIMSeq, and DEXSeq to perform a DTU analysis on simulated data. It also shows how to use stageR to perform two-stage testing of DTU, a statistical framework to screen at the gene level and then confirm which transcripts within the significant genes show evidence of DTU.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("rnaseqDTU")

Details

MaintainerMichael Love <michaelisaiahlove@gmail.com>
AuthorMichael Love [aut, cre], Charlotte Soneson [aut], Rob Patro [aut]
LicenseArtistic-2.0
URLhttps://github.com/thelovelab/rnaseqDTU/
Downloads rank151
Source branchdevel
biocViewsGeneExpressionWorkflow, ImmunoOncologyWorkflow, Workflow

Download

Follow the installation instructions to use this package in your R session.

Source packagernaseqDTU_1.33.0.tar.gz
Dependencies

Depends: R (>= 3.5.0), DRIMSeq, DEXSeq, stageR, DESeq2, edgeR, rafalib, devtools

Suggests: knitr, rmarkdown