vulcan

VirtUaL ChIP-Seq data Analysis using Networks

Bioconductor version: 3.24 · Package version: 1.35.1

Vulcan (VirtUaL ChIP-Seq Analysis through Networks) is a package that interrogates gene regulatory networks to infer cofactors significantly enriched in a differential binding signature coming from ChIP-Seq data. In order to do so, our package combines strategies from different BioConductor packages: DESeq for data normalization, ChIPpeakAnno and DiffBind for annotation and definition of ChIP-Seq genomic peaks, csaw to define optimal peak width and viper for applying a regulatory network over a differential binding signature.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("vulcan")