pepVet

Evaluate Proteolytic Digests for Proteomics Workflows

Bioconductor version: 3.24 · Package version: 0.99.1

Simulates proteolytic digestion, scores the resulting peptides for LC-MS/MS suitability, compares candidate enzymes, and reports digest quality at the protein level. Supports 40 cleaver-compatible enzyme rules, workflow presets, peptide mass and pI calculations, sequence-local cleavage-efficiency annotations, and proteome-aware uniqueness scoring. Evaluates multi-FASTA files in batches with per-protein triage and proteome-level summaries. Exports peptide lists for Skyline and generic downstream tools and prints styled console reports.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("pepVet")