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edge

Extraction of Differential Gene Expression

Bioconductor version: 3.24 · Package version: 2.45.0

The edge package implements methods for carrying out differential expression analyses of genome-wide gene expression studies. Significance testing using the optimal discovery procedure and generalized likelihood ratio tests (equivalent to F-tests and t-tests) are implemented for general study designs. Special functions are available to facilitate the analysis of common study designs, including time course experiments. Other packages such as sva and qvalue are integrated in edge to provide a wide range of tools for gene expression analysis.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("edge")

Details

MaintainerJohn D. Storey <jstorey@princeton.edu>, Andrew J. Bass <ajbass@emory.edu>
AuthorJohn D. Storey, Jeffrey T. Leek and Andrew J. Bass
LicenseMIT + file LICENSE
URLhttps://github.com/jdstorey/edge
Bug Reportshttps://github.com/jdstorey/edge/issues
Downloads rank575
Source branchdevel
biocViewsDataImport, DifferentialExpression, GeneExpression, MultipleComparison, Regression, Software, TimeCourse

Documentation

Download

Follow the installation instructions to use this package in your R session.

Source packageedge_2.45.0.tar.gz
Windows binary (x86_64)edge_2.45.0.zip
macOS binary (arm64)edge_2.45.0.tgz
macOS binary (x86_64)edge_2.45.0.tgz
Dependencies

Depends: R (>= 3.1.0), Biobase

Imports: methods, splines, sva, qvalue (>= 1.99.0), MASS

Suggests: testthat, knitr, ggplot2, reshape2