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appreci8R

appreci8R: an R/Bioconductor package for filtering SNVs and short indels with high sensitivity and high PPV

Bioconductor version: 3.24 · Package version: 1.31.0

The appreci8R is an R version of our appreci8-algorithm - A Pipeline for PREcise variant Calling Integrating 8 tools. Variant calling results of our standard appreci8-tools (GATK, Platypus, VarScan, FreeBayes, LoFreq, SNVer, samtools and VarDict), as well as up to 5 additional tools is combined, evaluated and filtered.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("appreci8R")

Details

MaintainerSarah Sandmann <sarah.sandmann@uni-muenster.de>
AuthorSarah Sandmann
LicenseLGPL-3
Downloads rank536
Source branchdevel
biocViewsGeneticVariability, SNP, Sequencing, Software, VariantAnnotation, VariantDetection

Download

Follow the installation instructions to use this package in your R session.

Source packageappreci8R_1.31.0.tar.gz
Windows binary (x86_64)appreci8R_1.31.0.zip
macOS binary (arm64)appreci8R_1.31.0.tgz
macOS binary (x86_64)appreci8R_1.31.0.tgz
Dependencies

Imports: shiny, shinyjs, DT, VariantAnnotation, BSgenome, BSgenome.Hsapiens.UCSC.hg19, TxDb.Hsapiens.UCSC.hg19.knownGene, Homo.sapiens, SNPlocs.Hsapiens.dbSNP144.GRCh37, XtraSNPlocs.Hsapiens.dbSNP144.GRCh37, Biostrings, MafDb.1Kgenomes.phase3.hs37d5, MafDb.ExAC.r1.0.hs37d5, MafDb.gnomADex.r2.1.hs37d5, COSMIC.67, rentrez, PolyPhen.Hsapiens.dbSNP131, SIFT.Hsapiens.dbSNP137, seqinr, openxlsx, Rsamtools, stringr, stats, GenomicRanges, S4Vectors, GenomicFeatures, IRanges, GenomicScores, SummarizedExperiment

Suggests: GO.db, org.Hs.eg.db, utils