airpart

Differential cell-type-specific allelic imbalance

Bioconductor version: 3.24 · Package version: 1.21.0

Airpart identifies sets of genes displaying differential cell-type-specific allelic imbalance across cell types or states, utilizing single-cell allelic counts. It makes use of a generalized fused lasso with binomial observations of allelic counts to partition cell types by their allelic imbalance. Alternatively, a nonparametric method for partitioning cell types is offered. The package includes a number of visualizations and quality control functions for examining single cell allelic imbalance datasets.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("airpart")