RCAS
RNA Centric Annotation System
Bioconductor version: 3.24 · Package version: 1.39.0
RCAS is an R/Bioconductor package designed as a generic reporting tool for the functional analysis of transcriptome-wide regions of interest detected by high-throughput experiments. Such transcriptomic regions could be, for instance, signal peaks detected by CLIP-Seq analysis for protein-RNA interaction sites, RNA modification sites (alias the epitranscriptome), CAGE-tag locations, or any other collection of query regions at the level of the transcriptome. RCAS produces in-depth annotation summaries and coverage profiles based on the distribution of the query regions with respect to transcript features (exons, introns, 5'/3' UTR regions, exon-intron boundaries, promoter regions). Moreover, RCAS can carry out functional enrichment analyses and discriminative motif discovery.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("RCAS") Details
| Maintainer | Bora Uyar <bora.uyar@mdc-berlin.de> |
| Author | Bora Uyar [aut, cre], Dilmurat Yusuf [aut], Ricardo Wurmus [aut], Altuna Akalin [aut] |
| License | Artistic-2.0 |
| System Requirements | pandoc (>= 1.12.3) |
| Downloads rank | 664 |
| Source branch | devel |
| biocViews | Coverage, GO, GeneSetEnrichment, GeneTarget, GenomeAnnotation, MotifAnnotation, MotifDiscovery, Software, Transcriptomics |
Download
Follow the installation instructions to use this package in your R session.
| Source package | RCAS_1.39.0.tar.gz |
| Windows binary (x86_64) | RCAS_1.39.0.zip |
| macOS binary (arm64) | RCAS_1.39.0.tgz |
| macOS binary (x86_64) | RCAS_1.39.0.tgz |
Dependencies
Depends: R (>= 3.5.0), plotly (>= 4.5.2), DT (>= 0.2), data.table
Imports: GenomicRanges, IRanges, BSgenome, BSgenome.Hsapiens.UCSC.hg19, GenomeInfoDb (>= 1.12.0), Biostrings, rtracklayer, GenomicFeatures, txdbmaker, rmarkdown (>= 0.9.5), genomation (>= 1.5.5), knitr (>= 1.12.3), BiocGenerics, S4Vectors, plotrix, pbapply, RSQLite, proxy, pheatmap, ggplot2, cowplot, seqLogo, utils, ranger, gprofiler2
Suggests: testthat, covr, BiocManager
Reverse dependencies
Imports Me (1): GenomicPlot