GOTHiC
Binomial test for Hi-C data analysis
Bioconductor version: 3.24 · Package version: 1.49.0
This is a Hi-C analysis package using a cumulative binomial test to detect interactions between distal genomic loci that have significantly more reads than expected by chance in Hi-C experiments. It takes mapped paired NGS reads as input and gives back the list of significant interactions for a given bin size in the genome.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("GOTHiC") Details
| Maintainer | Borbala Mifsud <b.mifsud@qmul.ac.uk> |
| Author | Borbala Mifsud and Robert Sugar |
| License | GPL-3 |
| Downloads rank | 766 |
| Source branch | devel |
| biocViews | Epigenetics, HiC, ImmunoOncology, Preprocessing, Sequencing, Software |
Documentation
Download
Follow the installation instructions to use this package in your R session.
| Source package | GOTHiC_1.49.0.tar.gz |
| Windows binary (x86_64) | GOTHiC_1.49.0.zip |
| macOS binary (arm64) | GOTHiC_1.49.0.tgz |
| macOS binary (x86_64) | GOTHiC_1.49.0.tgz |
Dependencies
Depends: R (>= 3.5.0), methods, GenomicRanges, Biostrings, BSgenome, data.table
Imports: BiocGenerics, S4Vectors (>= 0.9.38), IRanges, Rsamtools, ShortRead, rtracklayer, ggplot2, BiocManager, grDevices, utils, stats, Seqinfo
Suggests: HiCDataLymphoblast
Enhances: parallel