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DominoEffect

Identification and Annotation of Protein Hotspot Residues

Bioconductor version: 3.24 · Package version: 1.33.0

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DominoEffect")

Details

MaintainerMarija Buljan <marija.buljan.2@gmail.com>, Peter Blattmann <peter_blattmann@bluewin.ch>
AuthorMarija Buljan and Peter Blattmann
LicenseGPL (>= 3)
Downloads rank472
Source branchdevel
biocViewsAlignment, Proteomics, SequenceMatching, Software, SomaticMutation

Download

Follow the installation instructions to use this package in your R session.

Source packageDominoEffect_1.33.0.tar.gz
Windows binary (x86_64)DominoEffect_1.33.0.zip
macOS binary (arm64)DominoEffect_1.33.0.tgz
macOS binary (x86_64)DominoEffect_1.33.0.tgz
Dependencies

Depends: R (>= 3.5)

Imports: biomaRt, data.table, utils, stats, Biostrings, pwalign, SummarizedExperiment, VariantAnnotation, AnnotationDbi, Seqinfo, IRanges, GenomicRanges, methods

Suggests: knitr, testthat, rmarkdown