Package: MIRA
Version: 1.35.0
Date: 2021-11-21
Title: Methylation-Based Inference of Regulatory Activity
Description: DNA methylation contains information about the regulatory
        state of the cell. MIRA aggregates genome-scale DNA methylation
        data into a DNA methylation profile for a given region set with
        shared biological annotation. Using this profile, MIRA infers
        and scores the collective regulatory activity for the region
        set. MIRA facilitates regulatory analysis in situations where
        classical regulatory assays would be difficult and allows
        public sources of region sets to be leveraged for novel insight
        into the regulatory state of DNA methylation datasets.
Authors@R: c(person("Nathan", "Sheffield", role=c("aut")),
	person("John", "Lawson", email="jtl2hk@virginia.edu", role=c("aut", "cre")),
	person("Christoph", "Bock", role=c("ctb")))
Author: Nathan Sheffield <http://www.databio.org> [aut], Christoph Bock
        [ctb], John Lawson [aut, cre]
Maintainer: John Lawson <jtl2hk@virginia.edu>
Depends: R (>= 3.5)
Imports: BiocGenerics, S4Vectors, IRanges, GenomicRanges, data.table,
        ggplot2, Biobase, stats, bsseq, methods
Suggests: knitr, parallel, testthat, BiocStyle, rmarkdown,
        AnnotationHub, LOLA
VignetteBuilder: knitr
License: GPL-3
biocViews: ImmunoOncology, DNAMethylation, GeneRegulation,
        GenomeAnnotation, SystemsBiology, FunctionalGenomics, ChIPSeq,
        MethylSeq, Sequencing, Epigenetics, Coverage
URL: http://databio.org/mira
BugReports: https://github.com/databio/MIRA
RoxygenNote: 6.1.0
Config/pak/sysreqs: make libbz2-dev liblzma-dev libxml2-dev libssl-dev
        xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:46:33 UTC
RemoteUrl: https://github.com/bioc/MIRA
RemoteRef: HEAD
RemoteSha: bd35b236f8435f090585331c8662642f73f2a022
NeedsCompilation: no
Packaged: 2026-05-30 09:40:51 UTC; root
Built: R 4.6.0; ; 2026-05-30 14:00:29 UTC; unix
